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Lung Cancer Unveiled: Exploring Squamous Cell, Adenocarcinoma, Large Cell, and Small Cell Carcinomas

What kind of cancer is squamous cell carcinoma? You've heard of lung cancer, gastric cancer, breast cancer... What kind of cancer is squamous cell carcinoma? In fact, it can exist in multiple parts of the human body. It is derived from the mutation of squamous cells in the body. This has to start from the "source" of cancer.
Cancer is a general term and is considered to be a type of disease that originates from cell mutations. Relevant studies have found that mutations caused by DNA replication errors account for about 2/3 of the total number of human cancer mutations. Tissues with a high number of cell divisions have a relatively high chance of developing tumors. Therefore, squamous cell carcinoma (squamous cell carcinoma), adenocarcinoma, large cell carcinoma, small cell carcinoma, etc. are all classifications of malignant tumors based on different histopathologies.

Taking lung cancer as an example, the main types of malignant tumors in the lungs are squamous cell carcinoma, adenocarcinoma, large cell lung cancer and small cell lung cancer, and the first three can be collectively referred to as non-small cell lung cancer. For example, Li Lei is the English class representative, squadron leader, and extracurricular interest group leader in the class. When these titles are mentioned, they all refer to Li Lei. But when it comes to English class representatives, there will be one in every class in the school, not just Li Lei.

Let's get back to the point. Squamous cell carcinoma, as the name suggests, squamous cells have "mutated". Its location is commonly found in the skin, appendages, and mucous membranes. In layman's terms, the parts that are in direct contact with food and air are more susceptible to disease, such as the skin, esophagus, cervix, vagina, and other parts covered with squamous epithelium. It can also be seen in the bronchi, bladder, renal pelvis, etc.

The epidemiology of squamous cell carcinoma in each organ system is different. The more representative ones are:
Lung squamous cell carcinoma accounts for about 30%-35% of all lung cancer patients, mainly central lung cancer, and peripheral squamous cell carcinoma is less common. It mostly originates from the segmental and subsegmental bronchial mucosa and is common in elderly men.
The incidence of esophageal squamous cell carcinoma in my country is high, accounting for more than 90%, mainly occurring in the Taihang Mountains, Qinling Mountains, and the border area between Fujian and Guangdong.
Oral and maxillofacial squamous cell carcinoma accounts for about 58.6% of maxillofacial malignant tumors. The vast majority of malignant foot tumors occurring in the oral mucosa are squamous cell carcinomas, which are generally more common in the gums, tongue, cheeks, floor of mouth, hard palate, and lips. They often occur in the elderly, especially in men.
Eyelid squamous cell carcinoma ranks third among the three common eyelid epithelial malignancies. It is common in middle-aged and elderly patients, and can occur in both the upper and lower eyelids, but is more common in the lower eyelids. It is especially prone to the transition between the eyelid margin skin and mucosa.
Whether it is squamous cell carcinoma or adenocarcinoma, I hope they will not come to me. However, the prevention and control of malignant tumors remains severe. In my country, the incidence and mortality rates of lung cancer, liver cancer, gastric cancer, esophageal cancer, cervical cancer, etc., which are common in developing countries, are relatively high. At the same time, colorectal cancer, prostate cancer, and thyroid cancer, which are common in developed countries, have also increased significantly in recent years.

 

As the first person responsible for our own health, what can we do to prevent malignant tumors?
Smoking control
It is well known that about 30% of cancers are related to smoking. At present, there are about 320 million smokers in China, consuming more than 40% of the world's tobacco, and the number of smokers is on the rise. Smoking causes 23%-25% of cancer-related deaths. As long as strong tobacco control measures are taken, the incidence and mortality of lung cancer and related cancers in my country will be effectively reduced.

Vaccination
According to statistics, 1/5 of cancers in the world are caused by chronic infections, such as cervical cancer caused by human papillomavirus and liver cancer caused by hepatitis B virus. HPV vaccine has played an important role in eliminating cervical cancer. The effective use of multiple vaccines will effectively reduce the incidence and mortality of cancer in my country.

Improve lifestyle
Scientific research has confirmed that the cause of most cancers is related to lifestyle, while genetics and environment only account for 14% and 9% respectively. Therefore, in the etiology classification, this type of cancer has been classified as "lifestyle cancer". 1/3 of tumors are mainly caused by four lifestyle factors, including smoking, unhealthy diet, drinking and obesity. Choosing a scientific lifestyle and getting rid of bad habits can effectively prevent cancer.

Targeted early diagnosis and treatment, timely intervention of precancerous lesions
The World Health Organization pointed out that 40% of cancers are preventable, and 40% of cancers can be cured through early detection, early diagnosis, and early treatment. Early detection of lung cancer, liver cancer, and gastric cancer can also greatly increase the cure rate, so early diagnosis and treatment of cancer is very important. Strengthen the early diagnosis of cancer lesions and kill cancer in the cradle.

Deep integration of standardized diagnosis and treatment with precision medicine, an important means to reduce cancer mortality
The concept of standardized diagnosis and treatment of malignant tumors has long been recognized by the World Health Organization and the international medical community. By promoting standardized diagnosis and treatment of tumors, the level of tumor diagnosis and treatment will be greatly improved and the tumor mortality rate will be reduced. Precision medicine is the direction of change in human medicine. With the continuous breakthroughs in the technology of genetic diagnosis and treatment, the precise formulation of diagnosis and treatment plans based on the gene mutation information in different tumors can minimize the mortality of cancer patients.

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