In recent years, various types of anti-tumor drugs such as molecular targeted drugs and immunotherapy drugs have emerged continuously. However, chemotherapy drugs remain an indispensable and important treatment modality in current anti-tumor drug therapies. However, chemotherapy-induced nausea and vomiting (CINV) remains one of the most common side effects experienced by cancer patients after chemotherapy.
CINV can lead to dehydration, metabolic disorders, loss of appetite, decreased physical strength, wound dehiscence, esophageal tears, and other consequences. It can also increase patients' fear of treatment and reduce compliance with anti-tumor therapy, and in severe cases, even lead to treatment discontinuation.
Causes of CINV
The etiology of CINV is multifactorial, and the severity varies from person to person. For example, the type of medication used, chemotherapy drugs with a high emetic risk can lead to acute vomiting in ≥90% of patients, while those with moderate emetic risk can lead to acute vomiting in 30-90% of patients. In addition, individual factors such as gender, age, history of motion sickness, history of anxiety disorders, history of vomiting during previous chemotherapy, anticipatory nausea and vomiting, history of morning sickness during pregnancy, etc., can also affect the occurrence of CINV.
Management Approaches
1. Medication Therapy: Prophylactic medication is key to controlling nausea and vomiting. Doctors will prescribe different types of antiemetic drugs based on your condition and medication regimen. Through the appropriate use of antiemetic drugs, CINV can be effectively controlled.
2. Non-Pharmacological Therapies: In addition to medication, you can also try some non-pharmacological therapies, such as deep breathing and relaxation meditation, which can help alleviate bodily tension and discomfort. Additionally, appropriate physical exercise can also be helpful, such as walking, yoga, etc.
